Casting
It was unclear if Jodie Foster (Clarice Starling) and Anthony Hopkins (Hannibal Lecter) would reprise their respective roles for which they won Academy Awards in The Silence of the Lambs (best actress/actor). It became apparent that the producers and the studio could do without one of the original "stars" (and would go on to find a replacement). The withdrawal of both Foster and Hopkins could possibly have been terminal for the project, however. De Laurentiis confirmed this after the film's release: "First and foremost, I knew we had no movie without Anthony Hopkins."
Read more about this topic: Hannibal (film), Development
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