Princess Alice
Alice, Victoria's third child, passed it on to at least three of her children: Friedrich, Irene, and Alix.
- Prince Friedrich of Hesse and by Rhine (known in the family as "Frittie"). Died before his third birthday of bleeding on the brain resulting from a fall from a third-storey window (which would almost certainly have been fatal even if he had not had haemophilia).
- Princess Irene of Hesse and by Rhine (later Princess Heinrich of Prussia), passed it on to two of her three sons:
- Prince Waldemar of Prussia. Survived to age 56; had no issue.
- Prince Heinrich of Prussia. Died at age 4.
- Princess Alix of Hesse and by Rhine. Alix had a marriage proposal from Prince Albert Victor, eldest son of the future King Edward VII; had she accepted, haemophilia could have returned to the direct line of succession in Britain. Instead she married Tsar Nicholas II of Russia and passed it on to her only son:
- Tsarevitch Alexei. Murdered by the Bolsheviks at the age of 13, along with his parents and all four of his sisters. Alexei's haemophilia was one of the factors contributing to the collapse of Imperial Russia during the Russian Revolution of 1917. DNA testing of the Romanov family remains in 2009 showed that one of the four daughters, thought to be Maria by American researchers and Anastasia by Russian researchers, was a carrier. Grand Duchess Maria was thought by some to have been a symptomatic carrier because she haemorrhaged during a tonsillectomy.
- Princess Victoria of Hesse and by Rhine (later Victoria, Marchioness of Milford Haven), Alice's oldest child and maternal grandmother to Prince Philip, Duke of Edinburgh, might have inherited the mutation, though if so the gene remained hidden for several generations before possibly reappearing in the descendants of her eldest granddaughter, Princess Margarita of Greece and Denmark (see below).
- Princess Elizabeth of Hesse and by Rhine (later Grand Duchess Elizabeth Feodorovna of Russia), may or may not have been a carrier. She was childless when killed by the Bolsheviks in 1918.
- Princess Marie of Hesse and by Rhine, Alice's seventh and last child, may or may not have been a carrier. She died of diphtheria at the age of four.
Read more about this topic: Haemophilia In European Royalty
Famous quotes containing the words princess and/or alice:
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—Bible: Hebrew Lamentations 1:1.
Said of Jerusalem.
““I couldn’t afford to learn it,” said the Mock Turtle with a sigh. “I only took the regular course.”
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—Lewis Carroll [Charles Lutwidge Dodgson] (1832–1898)