GVB can stand for:
- Gaither Vocal Band, a Grammy Award winning Southern Gospel Music group
- Garibaldi Volcanic Belt, a chain of volcanoes in southwestern British Columbia, Canada
- Gemeentelijk Vervoerbedrijf, a municipal transport company in Amsterdam
- Generalized Valence Bond, a method in computational chemistry
- Giovanni van Bronckhorst, a Dutch footballer
- Godzilla vs. Biollante, 1989 film
- Good versus Bad, a strategy game
- Golfvaardigheidsbewijs or in English, a "golf license"
- Grover Beach (Amtrak station), California, United States; Amtrak station code GVB
- Graz AG Verkehrsbetriebe, the public transport agency in Graz, Austria