Growth Factor - Classes of Growth Factors

Classes of Growth Factors

Individual growth factor proteins tend to occur as members of larger families of structurally and evolutionarily related proteins. There are many families, which are listed below:

This list is incomplete; you can help by expanding it.
  • Adrenomedullin (AM)
  • Angiopoietin (Ang)
  • Autocrine motility factor
  • Bone morphogenetic proteins (BMPs)
  • Brain-derived neurotrophic factor (BDNF)
  • Epidermal growth factor (EGF)
  • Erythropoietin (EPO)
  • Fibroblast growth factor (FGF)
  • Glial cell line-derived neurotrophic factor (GDNF)
  • Granulocyte colony-stimulating factor (G-CSF)
  • Granulocyte macrophage colony-stimulating factor (GM-CSF)
  • Growth differentiation factor-9 (GDF9)
  • Hepatocyte growth factor (HGF)
  • Hepatoma-derived growth factor (HDGF)
  • Insulin-like growth factor (IGF)
  • Migration-stimulating factor
  • Myostatin (GDF-8)
  • Nerve growth factor (NGF) and other neurotrophins
  • Platelet-derived growth factor (PDGF)
  • Thrombopoietin (TPO)
  • Transforming growth factor alpha(TGF-α)
  • Transforming growth factor beta(TGF-β)
  • Tumor_necrosis_factor-alpha(TNF-α)
  • Vascular endothelial growth factor (VEGF)
  • Wnt Signaling Pathway
  • placental growth factor (PlGF)
  • (FBS)
  • IL-1- Cofactor for IL-3 and IL-6. Activates T cells.
  • IL-2- T-cell growth factor. Stimulates IL-1 synthesis. Activates B-cells and NK cells.
  • IL-3- Stimulates production of all non-lymphoid cells.
  • IL-4- Growth factor for activated B cells, resting T cells, and mast cells.
  • IL-5- Induces differentiation of activated B cells and eosinophils.
  • IL-6- Stimulates Ig synthesis. Growth factor for plasma cells.
  • IL-7- Growth factor for pre-B cells.


Stimulates cell cycle from G0 phase to G1 phase

Read more about this topic:  Growth Factor

Famous quotes containing the words classes of, classes, growth and/or factors:

    “There are two classes of men called poets. The one cultivates life, the other art,... one satisfies hunger, the other gratifies the palate.”
    —Henry David Thoreau (1817–1862)

    “I have no doubt but that the misery of the lower classes will be found to abate whenever the Government assumes a freer aspect and the laws favor a subdivision of Property.”
    —James Madison (1751–1836)

    “A personality is an indefinite quantum of traits which is subject to constant flux, change, and growth from the birth of the individual in the world to his death. A character, on the other hand, is a fixed and definite quantum of traits which, though it may be interpreted with slight differences from age to age and actor to actor, is nevertheless in its essentials forever fixed.”
    —Hubert C. Heffner (1901–1985)

    “Girls tend to attribute their failures to factors such as lack of ability, while boys tend to attribute failure to specific factors, including teachers’ attitudes. Moreover, girls avoid situations in which failure is likely, whereas boys approach such situations as a challenge, indicating that failure differentially affects self-esteem.”
    —Michael Lewis (late–20th-century)