The Grignard reaction (pronounced /ɡriɲar/) is an organometallic chemical reaction in which alkyl- or aryl-magnesium halides (Grignard reagents) add to a carbonyl group in an aldehyde or ketone. This reaction is an important tool for the formation of carbon–carbon bonds. The reaction of an organic halide with magnesium is not a Grignard reaction, but provides a Grignard reagent.
Grignard reactions and reagents were discovered by and are named after the French chemist François Auguste Victor Grignard (University of Nancy, France), who was awarded the 1912 Nobel Prize in Chemistry for this work. Grignard reagents are similar to organolithium reagents because both are strong nucleophiles that can form new carbon-carbon bonds.
Read more about Grignard Reaction: Reaction Mechanism, Preparation of Grignard Reagent, Degradation of Grignard Reagents, Industrial Use, Gallery
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