Grape Seed Extract - Dosage, Precautions and Interactions

Dosage, Precautions and Interactions

Oral grape seed extract is used in capsules or tablets usually containing 50 mg or 100 mg. Insufficient scientific information is known, however, about how long-term use of grape seed extract might affect health or any disease.

Side-effects and cautions, other NCCAM advisories.

  • In general, grape seed extract is well tolerated when taken by mouth, although it is better tolerated when encapsulated, as its taste is bitter. It has been used safely for up to 8 weeks in clinical trials.
  • Side-effects most often include headache, a dry, itchy scalp, dizziness, or nausea
  • Interactions between grape seed extract and medicines or other supplements have not been carefully studied

Due to the possible action of proanthocyanidins on limiting platelet adhesion, grape seed extract may act as a blood-thinner, increasing clotting time.

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