GPR may refer to:
- Derbi GPR125, a street motorcycle sold by Derbi
- Earth potential rise (also ground potential rise), when a large current flows to earth through an earth grid impedance
- General practice residency, a form of institution-based training for general dentistry
- General purpose register, a category of computer processor register
- Genius Populi Romani (Genius of the Roman People), a representation of the Roman concept of the genius
- Geophysical phase reader, a precise measuring instrument which reads electromagnetic signals emitted by the Earth
- Georgia Public Broadcasting (previously Georgia Public Radio), the public broadcasting radio and television state network in the U.S. state of Georgia
- Goldsworth Park Rangers F.C., a participating football club in the Surrey & Hants Border Football League Division 4
- Ground-penetrating radar, a geophysical method that uses radar pulses to image the subsurface
- Grupa na rzecz Partii Robotniczej, the Polish section of the Committee for a Workers' International