A gonadotropin-releasing hormone analogue (GnRH analogue or analog), also known as a luteinizing hormone releasing hormone agonist (LHRH agonist) or LHRH analogue is a synthetic peptide drug modeled after the human hypothalamic gonadotropin-releasing hormone (GnRH). A GnRH analogue is designed to interact with the GnRH receptor and modify the release of pituitary gonadotropins FSH and LH for therapeutic purposes. Shortly after the discovery of GnRH by Nobel laureates Guillemin and Schally researchers tried to modify the GnRH decapeptide with the intent to synthesize stimulating and blocking variants.
Two types of analogues have to be distinguished:
Read more about Gonadotropin-releasing Hormone Analogue: Agonists, Antagonists
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“Human language appears to be a unique phenomenon, without significant analogue in the animal world.”
—Noam Chomsky (b. 1928)