Historical Significance
Glycogen phosphorylase was the first allosteric enzyme to be discovered. This accomplishment was one of many landmark achievements made by Carl and Gerty Cori. In 1943, with the help of Arda Green, the pair illustrated that glycogen phosphorylase existed in either the a or b forms depending on its phosphorylation state, as well as in the R or T states based on the presences of AMP.
Read more about this topic: Glycogen Phosphorylase
Famous quotes containing the words historical and/or significance:
“We can imagine a society in which no one could survive as a social being because it does not correspond to biologically determined perceptions and human social needs. For historical reasons, existing societies might have such properties, leading to various forms of pathology.”
—Noam Chomsky (b. 1928)
“History is the interpretation of the significance that the past has for us.”
—Johan Huizinga (1872–1945)