Glutamate Antagonists
Ketamine and PCP were observed to produce significant similarities to schizophrenia. Ketamine produces more similar symptoms (hallucinations, withdrawal) without observed permanent effects (other than ketamine tolerance). PCP however is less representative symptomatically, but does appear to cause brain structure changes seen in schizophrenia. No drug has been found to induce schizophrenic symptoms completely, nor has been able to mimic developmental abnormalities.
Read more about this topic: Glutamate Hypothesis Of Schizophrenia
Famous quotes containing the word antagonists:
“There is a persuasion in the soul of man that he is here for cause, that he was put down in this place by the Creator to do the work for which he inspires him, that thus he is an overmatch for all antagonists that could combine against him.”
—Ralph Waldo Emerson (1803–1882)