Animal Models
A research done on mice in early 2009 has shown that when the neuregulin-1\ErbB post-synaptic receptor genes are deleted, the dendritic spines of glutamate neurons initially grow, but break down during later development. It was found that symptomic similarities to the disease matched schizophrenia upon expression.(symptoms such as disturbed social function, inability to adapt to predictable future stressors) This parallels the time delay for symptoms setting in with schizophrenic humans who usually appear to show normal development until early adulthood.
Read more about this topic: Glutamate Hypothesis Of Schizophrenia
Famous quotes containing the words animal and/or models:
“The hounding of a dog pursuing a fox or other animal in the horizon may have first suggested the notes of the hunting-horn to alternate with and relieve the lungs of the dog. This natural bugle long resounded in the woods of the ancient world before the horn was invented.”
—Henry David Thoreau (1817–1862)
“The parents who wish to lead a quiet life I would say: Tell your children that they are very naughty—much naughtier than most children; point to the young people of some acquaintances as models of perfection, and impress your own children with a deep sense of their own inferiority. You carry so many more guns than they do that they cannot fight you. This is called moral influence and it will enable you to bounce them as much as you please.”
—Samuel Butler (1835–1902)