Glycolysis
If the cell needs energy or carbon skeletons for synthesis then glucose 6-phosphate is targeted for glycolysis. Glucose 6-phosphate is first isomerized to fructose 6-phosphate by phosphoglucose isomerase.
| α--Glucose 6-phosphate | Phosphoglucose isomerase | β--Fructose 6-phosphate | |
| Phosphoglucose isomerase | |||
Compound C00668 at KEGG Pathway Database. Enzyme 5.3.1.9 at KEGG Pathway Database. Compound C05345 at KEGG Pathway Database. Reaction R00771 at KEGG Pathway Database.
This reaction converts glucose 6-phosphate to fructose 6-phosphate in preparation for phosphorylation to Fructose-1,6-bisphosphate. The addition of the 2nd phosphoryl group to produce Fructose-1,6-bisphosphate is an irreversible step, and so is used to irreversibly target the glucose 6-phosphate breakdown to provide energy for ATP production via glycolysis.
Read more about this topic: Glucose 6-phosphate