GLO1 - Gene

Gene

Glyoxalase I

Available structures

PDB

Ortholog search: PDBe, RCSB

List of PDB id codes
1BH5, 1FRO, 1QIN, 1QIP, 3VW9

Identifiers

Symbols

GLO1; GLOD1; GLYI

External IDs

OMIM: 138750 MGI: 95742 HomoloGene: 4880 ChEMBL: 2424 GeneCards: GLO1 Gene

EC number

4.4.1.5

Gene Ontology
Molecular function	• lactoylglutathione lyase activity • metal ion binding
Cellular component	• cytoplasm
Biological process	• carbohydrate metabolic process • regulation of transcription from RNA polymerase II promoter • glutathione metabolic process • methylglyoxal metabolic process • negative regulation of apoptotic process
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez

2739

109801

Ensembl

ENSG00000124767

ENSMUSG00000024026

UniProt

Q04760

Q9CPU0

RefSeq (mRNA)

NM_006708

NM_001113560

RefSeq (protein)

NP_006699

NP_001107032

Location (UCSC)

Chr 6:
38.64 – 38.67 Mb

Chr 17:
30.59 – 30.61 Mb

PubMed search

Lactoylglutathione lyase in humans is encoded by the GLO1 gene.