GLB1

GLB1

Identifiers Symbols GLB1; EBP; ELNR1; MPS4B External IDs OMIM: 611458 MGI: 88151 HomoloGene: 47922 ChEMBL: 2522 GeneCards: GLB1 Gene EC number 3.2.1.23

Gene Ontology
Molecular function	• beta-galactosidase activity • protein binding • galactoside binding • cation binding
Cellular component	• lysosomal lumen • perinuclear region of cytoplasm
Biological process	• carbohydrate metabolic process • glycosaminoglycan catabolic process • phospholipid metabolic process • sphingolipid metabolic process • glycosphingolipid metabolic process • galactose catabolic process • glycosaminoglycan metabolic process • keratan sulfate metabolic process • keratan sulfate catabolic process • small molecule metabolic process
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 2720 12091 Ensembl ENSG00000170266 ENSMUSG00000045594 UniProt P16278 P23780 RefSeq (mRNA) NM_000404 NM_009752 RefSeq (protein) NP_000395 NP_033882 Location (UCSC) Chr 3:
33.04 – 33.14 Mb Chr 9:
114.4 – 114.47 Mb PubMed search

Galactosidase, beta 1, also known as GLB1, is a protein which in humans is encoded by the GLB1 gene.

The GLB1 protein is a beta-galactosidase that cleaves the terminal beta-galactose from ganglioside substrates and other glycoconjugates. The GLB1 gene also encodes an elastin binding protein.

In corn (Zea mays), Glb1 is a gene coding for the storage protein globulin.