Gitter Cell - Role of Microglia in Neurodegeneration

Role of Microglia in Neurodegeneration

Neurodegenerative disorders are characterized by progressive cell loss in specific neuronal populations. "Many of the normal trophic functions of glia may be lost or overwhelmed when the cells become chronically activated in progressive neurodegenerative disorders, for there is abundant evidence that in such disorders, activated glia play destructive roles by direct and indirect inflammatory attack." The following are prominent examples of microglial cells' role in neurodegenerative disorders.

Read more about this topic:  Gitter Cell

Famous quotes containing the words role of and/or role:

    The role of the intelligence—that part of us which affirms and denies and formulates opinions—is merely to submit.
    Simone Weil (1909–1943)

    Recent studies that have investigated maternal satisfaction have found this to be a better prediction of mother-child interaction than work status alone. More important for the overall quality of interaction with their children than simply whether the mother works or not, these studies suggest, is how satisfied the mother is with her role as worker or homemaker. Satisfied women are consistently more warm, involved, playful, stimulating and effective with their children than unsatisfied women.
    Alison Clarke-Stewart (20th century)