Surname
- Gillespie
- A. Arnold Gillespie (1899-1978), American cinema special effects artist
- Aaron Gillespie (born 1983), American rock singer & drummer
- Alastair Gillespie (born 1922), Canadian politician
- Alessa Gillespie, character from the Silent Hill series
- Archibald H. Gillespie (1810-1873), officer in the United States Marine Corps
- Billy Gillespie (1891-1981), Irish football (soccer) player
- Bobby Gillespie (born 1964), Scottish rock and roll musician
- Brock Gillespie (born 1983), professional basketball player
- Craig Gillespie (born 1967), Australian film director
- Dahlia Gillespie, character from the Silent Hill series
- Dan Gillespie, mathematical chemist
- Dan Gillespie Sells (born 1979), English singer
- Dana Gillespie (born 1949), British actress and singer
- Darlene Gillespie (born 1941), Mousekateer born in Canada
- David Gillespie, Australian rugby league footballer
- Dean M. Gillespie (1884-1949), American politician
- Dizzy Gillespie (1917-1993), American jazz musician
- Earl Gillespie (1922-2003), American sportscaster
- Ed Gillespie (born 1962), American lobbyist
- Gary Gillespie (born 1960), Scottish footballer
- George Gillespie (1613-1648), Scottish theologian
- George Lewis Gillespie, Jr. (1841-1913), US Army officer
- Gina Gillespie (born 1951), American actress
- Jacqueline Pascarl-Gillespie (born 1963), Australian author
- James Gillespie (c.1747-1805), American politician
- Jason Gillespie (born 1975), Australian cricketer
- John H. Gillespie, American evolutionary biologist
- Keith Gillespie (born 1975), Northern Irish footballer
- Kevin Gillespie (disambiguation)
- Margaret V. Gillespie (born 1969), American politician
- Mark Gillespie (disambiguation)
- Mike Gillespie (disambiguation)
- Mitch Gillespie, American politician
- Nick Gillespie (born 1963), American editor & political writer
- Paul Gillespie (1920-1970), Major League Baseball catcher
- Robert Gillespie
- Ronald Gillespie (born 1924), Canadian chemist
- Ross Gillespie (born 1935), New Zealand hockey player
- Shaun Gillespie, Canadian politician & new wave musician
- Steven Gillespie (born 1985), English footballer
- Stuart Gillespie (born 1957), New Zealand cricketer
- Thomas Gillespie (disambiguation)
- William Gillespie (disambiguation)
- Gillaspie
- Conor Gillaspie (born 1987), American baseball player
- Kayne Gillaspie (born 1979), American fashion designer
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