Research
Chrousos has focused his research on the hypothalamic-pituitary-adrenal (HPA) axis and has extensively studied the neuroendocrine alterations associated with mood disorders, sleep, pain perception, and immune function. In particular, he has worked on the glucocorticoid signaling system diseases of the HPA axis, such as Cushing’s syndrome, Addison’s disease, and congenital adrenal hyperplasia, and the physiologic and molecular mechanisms of stress. Early in his career, he described in the Journal of Clinical Investigation the Glucocorticoid Resistance Syndrome, a rare genetic disease of the glucocorticoid receptor that causes hypertension and hyperandrogenism in children and adults . Subsequently, he has contributed the majority of the international original publications on this syndrome, which has served as a model of the study of the physiologic functions of these key steroid hormones that regulate the homeostasis of the organism.
Read more about this topic: George P. Chrousos
Famous quotes containing the word research:
“The working woman may be quick to see any problems with children as her fault because she isn’t as available to them. However, the fact that she is employed is rarely central to the conflict. And overall, studies show, being employed doesn’t have negative effects on children; carefully done research consistently makes this clear.”
—Grace Baruch (20th century)
“Our science has become terrible, our research dangerous, our findings deadly. We physicists have to make peace with reality. Reality is not as strong as we are. We will ruin reality.”
—Friedrich Dürrenmatt (1921–1990)
“Feeling that you have to be the perfect parent places a tremendous and completely unnecessary burden on you. If we’ve learned anything from the past half-century’s research on child development, it’s that children are remarkably resilient. You can make lots of mistakes and still wind up with great kids.”
—Lawrence Kutner (20th century)