George I may refer to:
- Patriarch George II of Alexandria (621–631)
- Patriarch George I of Constantinople (d. 686)
- George I of Georgia (1014–1027)
- George I of Russia, (c. 1099–1157)
- George I of Bulgaria (1280–1292)
- George I of Halych (c. 1252–1308)
- George I, Prince of Anhalt-Dessau (c. 1390-1474)
- George I, Landgrave of Hesse-Darmstadt (1547–1596)
- George I Rákóczi (1591–1648), prince of Transylvania
- George I of Great Britain (1660–1727), also served as Elector of Hanover
- George I of Greece (1845–1913)