The following airlines fly passenger services to George F. L. Charles Airport:
| Airlines | Destinations |
|---|---|
| Air Antilles | Fort-de-France |
| Air Caraïbes | Fort-de-France, Pointe-à-Pitre |
| Caribbean Airlines | Port of Spain |
| LIAT | Antigua, Barbados, Georgetown-Cheddi Jagan, Grenada, Port of Spain, Saint Vincent, San Juan, Sint Maarten, Dominica |
| SVG Air | Saint Vincent |
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