George Cavendish may refer to:
- George Cavendish, 1st Earl of Burlington (1754–1834), Member of the United Kingdom Parliament
- George Cavendish (writer) (circa 1494–1562), English writer
- George Henry Compton Cavendish (1784–1809), English politician
- Lord George Augustus Cavendish (died 1794), British politician
- Lord George Henry Cavendish (1810–1880), Member of the United Kingdom Parliament
- George Cavendish-Bentinck