History
In 1974 Rudolf Jaenisch created the first genetically modified animal by inserting a DNA virus into an early-stage mouse embryo and showing that the inserted genes were present in every cell. However the mice did not pass the transgene to their offspring. In 1981 the laboratories of Frank Ruddle from Yale, Frank Constantini and Elizabeth Lacy from Oxford, and Ralph Brinster and Richard Palmiter from University of Pennsylvania and University of Washington injected purified DNA into a single-cell mouse embryo and showed transmission of the genetic material to subsequent generations. During the early eighties the technology used to generate genetically modified mice was improved into a tractable and reproducible method.
Read more about this topic: Genetically Modified Mouse
Famous quotes containing the word history:
“These anyway might think it was important
That human history should not be shortened.”
—Robert Frost (1874–1963)
“History is more or less bunk. It’s tradition. We don’t want tradition. We want to live in the present and the only history that is worth a tinker’s damn is the history we make today.”
—Henry Ford (1863–1947)
“Look through the whole history of countries professing the Romish religion, and you will uniformly find the leaven of this besetting and accursed principle of action—that the end will sanction any means.”
—Samuel Taylor Coleridge (1772–1834)