Combined Approaches
Programs such as Maker combine extrinsic and ab initio approaches by mapping protein and EST data to the genome to validate ab initio predictions. Augustus, which may be used as part of the Maker pipeline, can also incorporate hints in the form of EST alignments or protein profiles to increase the accuracy of the gene prediction.
Read more about this topic: Gene Prediction
Famous quotes containing the words combined and/or approaches:
“Pregnant women! They had that weird frisson, an aura of magic that combined awkwardly with an earthy sense of duty. Mundane, because they were nothing unique on the suburban streets; ethereal because their attention was ever somewhere else. Whatever you said was trivial. And they had that preciousness which they imposed wherever they went, compelling attention, constantly reminding you that they carried the future inside, its contours already drawn, but veiled, private, an inner secret.”
—Ruth Morgan (1920–1978)
“A politician is a statesman who approaches every question with an open mouth.”
—Adlai Stevenson (1900–1965)