In enzymology, a GDP-glucosidase (EC 3.2.1.42) is an enzyme that catalyzes the chemical reaction
- GDP-glucose + H2O D-glucose + GDP
Thus, the two substrates of this enzyme are GDP-glucose and H2O, whereas its two products are D-glucose and GDP.
This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is GDP-glucose glucohydrolase. Other names in common use include guanosine diphosphoglucosidase, and guanosine diphosphate D-glucose glucohydrolase.