GCN may refer to:
- Nintendo GameCube, a video game console
- Gamma Ray Burst Coordinates Network, a system by which Gamma-Ray Burst information is relayed from the first responding observatory to the rest of the GRB community
- Grand Canyon National Park Airport, according to the International Air Transport Association airport code
- Global Christian Network, a religious broadcaster on AMC4 satellite television, a station in New York City and EICB TV across the US
- Gay Christian Network, nonprofit organization and its associated social networking site
- Gay Community News (Dublin), Ireland's longest running gay newspaper, published since 1988 by the National Lesbian and Gay Federation
- Gay Community News (Boston), a weekly journal published in Boston from 1973 to 1992
- Graphics Core Next Gen - AMD's GPU architecture.