GAS7

Identifiers Symbols GAS7; MLL/GAS7 External IDs OMIM: 603127 MGI: 1202388 HomoloGene: 69015 GeneCards: GAS7 Gene

Gene Ontology
Molecular function sequence-specific DNA binding transcription factor activity
actin filament binding
Cellular component ruffle
cytoplasm
actin filament
Biological process regulation of transcription, DNA-dependent
cell cycle arrest
regulation of cell shape
actin filament polymerization
neuron projection morphogenesis
actin filament bundle assembly
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 8522 14457 Ensembl ENSG00000007237 ENSMUSG00000033066 UniProt O60861 B1ATI9 RefSeq (mRNA) NM_001130831 NM_001109657 RefSeq (protein) NP_001124303 NP_001103127 Location (UCSC) Chr 17:
9.81 – 10.1 Mb Chr 11:
67.46 – 67.69 Mb PubMed search

Growth arrest-specific protein 7 is a protein that in humans is encoded by the GAS7 gene.

Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described.