Friedrich Daniel Von Recklinghausen - Contributions

Contributions

In 1882 Recklinghausen released a monograph which reviewed previous literature and characterized the tumors of Neurofibromatosis type I or NF-1 as neurofibromas, consisting of an intense commingling of nerve cells and fibrous tissue. NF-1 is sometimes referred to as "von Recklinghausen syndrome".

In 1889 he coined the term "haemochromatosis", and was the first to provide the link between haemochromatosis and iron accumulation in body tissue. Recklinghausen published these findings in a treatise titled Hämochromatose (1889). He also established a method of staining the lines of cell junctions with silver, a procedure that led to Julius Friedrich Cohnheim’s research on leukocyte migration and inflammation. In 1910, he coined the term oncosis (derived from ónkos, meaning swelling). This term is sometimes used to describe Ischemic cell death. In addition, he is credited with performing important studies on the heart and circulation.

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