Career in Medical Research and Education
Professor von Gudden was the judge in Nissl's college-essay competition, and he was so impressed with the study that he offered Nissl an assistantship at the Oberbayerische Kreis-Irrenanstalt Haar in Munich which von Gudden headed. Nissl accepted, and remained in that post from 1885 until 1888. In 1888 Nissl moved to the Institution Blankenheim. In 1889 he went to Frankfurt as second in position under Emil Sioli (1852–1922) at the Städtische Irrenanstalt. There he met neurologist Ludwig Edinger and neuropathologist Karl Weigert, who was developing a neuroglial stain. This work motivated Nissl to study mental and nervous diseases by relating them to observable changes in glial cells, blood elements, blood vessels and brain tissue in general.
In Frankfurt Nissl became acquainted with Alois Alzheimer, and they collaborated over seven years. They became close friends, jointly editing the Histologische und histopathologische Arbeiten über die Grosshirnrinde (1904–1921).
In 1895 Emil Kraepelin invited Nissl to become assistant physician at the University of Heidelberg. By 1904 he was a full professor at that institution, and became director of the Department of Psychiatry when Kraepelin moved to Munich.
Read more about this topic: Franz Nissl
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