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- Four Horsemen (Supreme Court), United States Supreme Court conservative justices during the New Deal era
- Former west coast boutique investment banks: Robertson Stephens, Alex. Brown & Sons, Hambrecht & Quist, and Montgomery Securities
- Four Horsemen (drink), a cocktail containing four hard liquors and named after the Four Horsemen of the Apocalypse
- "The Four Horsemen", an informal discussion on the "New Atheism" held in 2007 and its proponents: Richard Dawkins, Daniel C. Dennett, Sam Harris, and the late Christopher Hitchens.
- Four Horsemen (film), a 2012 documentary on the early 2000s Global Financial Crisis
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