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March and Williams each built cars with an identical 6-wheeled layout, but neither car was ever raced in F1. In both cases it was found that the cars were about the same as normal cars in terms of speed since the extra traction was negated by the added rolling resistance, although the March 2-4-0 was later to have some success in hillclimbs.
Nevertheless it is interesting to note that it was the Williams FW08D, rather than any 4-wheeled car, which prompted FISA to ban 4WD from Formula 1 in 1982.
Read more about this topic: Four-wheel Drive In Formula One