Folliculogenesis - Number of Follicles

Number of Follicles

Recently, two publications have challenged the idea that a finite number of follicles are set around the time of birth. Renewal of ovarian follicles from germline stem cells (originating from bone marrow and peripheral blood) was reported in the postnatal mouse ovary. Studies attempting to replicate these results are underway, but a study of populations in 325 human ovaries found no supporting evidence for follicular replenishment.

In 2010, researchers at the University of Edinburgh determined that by the time women are 30 years old, only 10% of their non-growing follicles (NGFs) remain. At birth, women have all their follicles for folliculogenesis, and they steadily decline until menopause.

Read more about this topic:  Folliculogenesis

Famous quotes containing the words number of and/or number:

    Today, almost forty years later, I grow dizzy when I recall that the number of manufactured tanks seems to have been more important to me than the vanished victims of racism.
    Albert Speer (1905–1981)

    A child’s self-image is more like a scrapbook than a single snapshot. As the child matures, the number and variety of images in that scrapbook may be far more important than any individual picture pasted inside it.
    Lawrence Kutner (20th century)