Follicular Dendritic Cells - New Development

New Development

Researches by Kristin Denzer and associates has shown that though the FDCs do not have MHC-II attached to there membrane directly, rather there are microvesicles attached to their membrane contain MHC II molecules. The size and marker profile of these microvesicles resembles that of exosomes. They have been shown to be activating Th cells invitro but the in vivo function is not confirmed.

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