Activity
FSH regulates the development, growth, pubertal maturation, and reproductive processes of the human body.
- In both males and females, FSH stimulates the maturation of germ cells.
- In males, FSH induces Sertoli cells to secrete inhibin and stimulates the formation of sertoli-sertoli tight junctions (zonula occludens).
- In females, FSH initiates follicular growth, specifically affecting granulosa cells. With the concomitant rise in inhibin B, FSH levels then decline in the late follicular phase. This seems to be critical in selecting only the most advanced follicle to proceed to ovulation. At the end of the luteal phase, there is a slight rise in FSH that seems to be of importance to start the next ovulatory cycle.
Like its partner LH, FSH release at the pituitary gland is controlled by pulses of gonadotropin-releasing hormone (GnRH). Those pulses, in turn, are subject to the oestrogen feed-back from the gonads.
Read more about this topic: Follicle-stimulating Hormone
Famous quotes containing the word activity:
“The animal is one with its life activity. It does not distinguish the activity from itself. It is its activity. But man makes his life activity itself an object of his will and consciousness. He has a conscious life activity. It is not a determination with which he is completely identified.”
—Karl Marx (1818–1883)
“In communist society, where nobody has one exclusive sphere of activity but each can become accomplished in any branch he wishes, society regulates the general production and thus makes it possible for me to do one thing today and another tomorrow, to hunt in the morning, fish in the afternoon, rear cattle in the evening, criticize after dinner, just as I have a mind, without ever becoming hunter, fisherman, shepherd or critic.”
—Karl Marx (1818–1883)
“The superstition respecting power and office is going to the ground. The stream of human affairs flows its own way, and is very little affected by the activity of legislators. What great masses of men wish done, will be done; and they do not wish it for a freak, but because it is their state and natural end.”
—Ralph Waldo Emerson (1803–1882)