Treatment
- Salt restriction and diuretics, such as furosemide, for edema
- Antihypertensives (especially ACEIs) – if the blood pressure is too high
- treat present hyperlipidemia (e.g. statins, fibrates; although fibrates are contraindicated in renal failure)
- Aldosterone antagonist to decrease proteinuria and thus offer a degree of reno-protection
- Angiotensin II receptor antagonist
- ACE inhibitor
- Corticosteroids, such as prednisone – based on the clinical judgment of physician (no broad consensus/guideline)
- Cytotoxics, such as cyclophosphamide may be used to induce remission in patients presenting with FSGS refractory to corticosteroids, or in patients who do not tolerate steroids.
- Plasmapheresis – blood cleansing using a machine to remove the patient's blood plasma and replacing it with donor plasma.
- Vitamin E
- Fish oil
- Immunosuppressive drugs
- None – sometimes none of the above works and the patient will require dialysis with possibly later transplantation of a new kidney.
Read more about this topic: Focal Segmental Glomerulosclerosis
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