Fluorapatite can be synthesized in a two step process. First, calcium phosphate is generated by combining calcium and phosphate salts at neutral pH.This material then reacts further with fluoride sources (often sodium monofluorophosphate or calcium fluoride (CaF2)) to give the mineral. This reaction is integral in the global phosphorus cycle.
- 3 Ca2+ + 2 PO3−
4 → Ca3(PO4)2
- 3 Ca3(PO4)2 + CaF2 → 2 Ca5(PO4)3F
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