Disadvantages of Flow
- Dedicated equipment is needed for precise continuous dosing (e.g. pumps), connections, etc.
- Start up and shut down procedures have to be established.
- Scale up of micro effects such as the high area to volume ratio is not straightforward and economy of scale may not apply. Typically, a scale up leads to a dedicated plant.
- Safety issues for the storage of reactive material still apply.
The drawbacks have been discussed in view of establishing small scale continuous production processes by Pashkova and Greiner.
Read more about this topic: Flow Chemistry
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