Major Intersections
| County | Location | Mile | km | Destinations | Notes | |||
|---|---|---|---|---|---|---|---|---|
| Putnam |
McMeekin | 0.0 | 0.0 | SR 20 / CR 20A | Southern terminus | |||
| CR 21 | ||||||||
| Melrose | SR 26 | |||||||
| Clay |
No major junctions | |||||||
| Bradford |
Keystone Heights | CR 21B | ||||||
| Clay |
SR 100 | |||||||
| Penney Farms | SR 16 | |||||||
| Middleburg | CR 215 | |||||||
| SR 23 | ||||||||
| Orange Park | SR 224 | |||||||
| Duval |
Jacksonville | I-295 / SR 9A | Exit 12 | |||||
| SR 134 | ||||||||
| SR 208 | ||||||||
| Cedar River Bridge | ||||||||
| SR 111 | ||||||||
| SR 128 | ||||||||
| 57.4 | 92.4 | US 17 / SR 15 | Northern terminus at partial cloverleaf interchange; Blanding Boulevard continues to Park Street | |||||
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi | ||||||||
Read more about this topic: Florida State Road 21
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