Filtered Air Positive Pressure

A filtered air positive pressure environment in laboratory animal science is a space that is under positive pressure with respect to the outside world. In this way, no germs that could affect the lab animals or that are a threat to the SPF status can enter the facility. To bring in new air, high efficiency particulate air filters (HEPA) are used.

In some facilities, the opposite is done: negative pressure inside prevents escape of germs to the outside world. This is done when the facility does research on dangerous germs like anthrax.

Next to these obvious things, these facilities can have other special hygiene control elements:

  • air locks for personnel, feed, bedding, cages and materials (e.g. autoclave with two doors, one to the inside, one to the outside)
  • showers for personnel
  • emergency power generator or uninterruptible power supplies

Famous quotes containing the words air, positive and/or pressure:

    Nature is a setting that fits equally well a comic or a mourning piece. In good health, the air is a cordial of incredible virtue. Crossing a bare common, in snow puddles, at twilight, under a clouded sky, without having in my thoughts any occurrence of special good fortune, I have enjoyed a perfect exhilaration. I am glad to the brink of fear.
    Ralph Waldo Emerson (1803–1882)

    If all political power be derived only from Adam, and be to descend only to his successive heirs, by the ordinance of God and divine institution, this is a right antecedent and paramount to all government; and therefore the positive laws of men cannot determine that, which is itself the foundation of all law and government, and is to receive its rule only from the law of God and nature.
    John Locke (1632–1704)

    Osteopath—One who argues that all human ills are caused by the pressure of hard bone upon soft tissue. The proof of his theory is to be found in the heads of those who believe it.
    —H.L. (Henry Lewis)