FHL1

FHL1

Identifiers Symbols FHL1; FHL-1; FHL1A; FHL1B; FLH1A; KYOT; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA External IDs OMIM: 300163 MGI: 1298387 HomoloGene: 31038 GeneCards: FHL1 Gene

Gene Ontology
Molecular function molecular_function
protein binding
zinc ion binding
ion channel binding
metal ion binding
Cellular component nucleus
cytoplasm
cytosol
plasma membrane
Biological process regulation of membrane depolarization
muscle organ development
organ morphogenesis
negative regulation of G2/M transition of mitotic cell cycle
cell differentiation
negative regulation of cell growth
positive regulation of potassium ion transport
regulation of potassium ion transmembrane transporter activity
negative regulation of G1/S transition of mitotic cell cycle
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 2273 14199 Ensembl ENSG00000022267 ENSMUSG00000023092 UniProt Q13642 P97447 RefSeq (mRNA) NM_001159699 NM_001077361 RefSeq (protein) NP_001153171 NP_001070829 Location (UCSC) Chr X:
135.23 – 135.29 Mb Chr X:
56.73 – 56.79 Mb PubMed search

Four and a half LIM domains protein 1 is a protein that in humans is encoded by the FHL1 gene.

LIM proteins, named for 'LIN11, ISL1, and MEC3,' are defined by the possession of a highly conserved double zinc finger motif called the LIM domain.

Read more about FHL1:  Role in Muscle Disorders