Fetal Trimethadione Syndrome - Characteristics

Characteristics

Fetal trimethadione syndrome is characterized by the following major symptoms as a result of the teratogenic characteristics of trimethadione.

  • Cranial and facial abnormalities which include; microcephaly, midfacial flattening, V-shaped eyebrows and a short nose
  • Cardiovascular abnormalities
  • Absent kidney and ureter
  • Meningocele, a birth defect of the spine
  • Omphalocele, a birth defect where portions of the abdominal contents project into the umbilical cord
  • A delay in mental and physical development

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