Federica may refer to:
- 12817 Federica (1996 FM16), a Main-belt Asteroid discovered in 1996
- Federica Constantini (born 1988), Italian figure skater
- Federica Faiella (born 1981), Italian ice dancer
- Federica Fontana (born 1977), Italian television sports announcer
- Federica Guzmán, (born 1981), the former Miss Venezuela World 2006
- Federica Haumuller (born 1972), Argentinian former professional tennis player
- Federica Montseny (1905–1994), Spanish anarchist, intellectual and Minister of Health
- Federica Pellegrini (born 1988), Italian swimmer
- Federica Ridolfi (born 1974), Italian dancer and a hostess on television
- Federica Sallusto (born 1961), Italian biologist
- Victoria Federica de Marichalar y de Borbón (born 2000), daughter of the Duchess and Duke of Lugo, and sixth in the line of succession to the Spanish throne
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