Fatty-acyl-Co A Synthase - Reaction

Reaction

The enzyme catalyzes the reaction:

Acetyl-CoA + n malonyl-CoA + 4n NADPH + 4n H+ long-chain-acyl-CoA + n CoA + n CO2 + 4n NADP+

The 4 substrates of this enzyme are acetyl-CoA, malonyl-CoA, NADPH, and H+, whereas its 4 products are Acyl-CoA, CoA, CO2, and NADP+.

More specifically, the FAS catalysis mechanism consumes a acetyl-coenzyme A (acetyl-CoA) and seven malonyl-CoA molecules to produce a Palmitoyl-CoA.

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