Background
Synthesis of fatty acids is generally performed by fatty acid synthase (FAS). Though the syntheses of fatty acids are very similar across all organisms, the enzymes and subsequent enzymatic mechanisms involved in fatty acid synthesis vary between eukaryotes and prokaryotes. There are two types of fatty acid synthesis (FAS) mechanisms: type I FAS and type II FAS. Type I FAS exists in eukaryotes, including mammalian cells and fungi. Type II FAS are found in prokaryotes. The type I FAS system utilizes a multi-enzyme complex, which are highly integrated, while the type II FAS system utilizes individual, separate enzymes to catalyze the reactions involved in fatty acid synthesis. Yeast fatty acyl synthase belongs to the Type I FAS and was the first of Type I FAS to be studied.
Read more about this topic: Fatty-acyl-Co A Synthase
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