Control of F. Magna and Prevention
For control of fascioloidosis in wild ruminants, successful application of anthelminthics in feed is necessary. The drug has to have flavour and smell that do not prevent animals from eating medicated feed. In addition, there should adequate therapeutic scope, i.e. span between therapeutic and minimal toxic dose. Therefore, only some of anthelminthics that are efficient in domestic ruminants have been tested in wild ruminants infected with F. magna. Several drugs, namely oxyclozanide, rafoxanide, albendazole, diamphenetide, closantel, clorsulon, and triclabendazole, have been used in control of F. magna infection in cervids. However, the results have differed between different authors. In the same way as for F. hepatica, triclabendazole seems to be the most effective against F. magna. Fascioloidosis of cervids was successfully controlled with triclabendazole in USA, and triclabendazole with levamizole in Hungary, Canada, Austria, and Croatia. In contrast, rafoxanide is commonly used in treatment in Czech Republic Slovakia and Hungary. Nevertheless, recent studies suggested that use of rafoxanide in control of F. magna infection should be considered. Unfortunately, rafoxanide in a commercial drug called Rafendazol Premix is the only registered drug for wild ruminants. Triclabendazole and others are produced as drugs for domestic animals and it can be used in free-living animals only with special permit.
Read more about this topic: Fascioloides Magna
Famous quotes containing the words control of, control and/or prevention:
“We long for our father. We wear his clothes, and actually try to fill his shoes. . . . We hang on to him, begging him to teach us how to do whatever is masculine, to throw balls or be in the woods or go see where he works. . . . We want our fathers to protect us from coming too completely under the control of our mothers. . . . We want to be seen with Dad, hanging out with men and doing men things.”
—Frank Pittman (20th century)
“America is neither free nor brave, but a land of tight, iron- clanking little wills, everybody trying to put it over everybody else, and a land of men absolutely devoid of the real courage of trust, trust in life’s sacred spontaneity. They can’t trust life until they can control it.”
—D.H. (David Herbert)
“... if this world were anything near what it should be there would be no more need of a Book Week than there would be a of a Society for the Prevention of Cruelty to Children.”
—Dorothy Parker (1893–1967)