O
- Mary Ann O'Brien: Ind Senator 2011–
- her first cousin-in-law John Magnier (born 1948): Ind Senator 1987–1989
- Richard O'Connell (1892–1964): CnaG TD Limerick 1923–1932
- his nephew Tom O'Donnell (born 1926): FG TD Limerick East 1961–1987, MEP Munster 1979–1989
- Tom's nephew Kieran O'Donnell (born 1963): FG TD Limerick East 2007–
- his nephew Tom O'Donnell (born 1926): FG TD Limerick East 1961–1987, MEP Munster 1979–1989
- O'Connor, see Connor
- O'Higgins, see Sullivan
- Pierce Mahony (1792–1853): Repeal MP Kinsale 1837
- his grandson Pierce O'Mahony (1850–1930): IPP MP North Meath 1886–1892
- his son Dermot O'Mahony (1881–1960): CnaG TD Wicklow 1927–1938
- his grandson Pierce O'Mahony (1850–1930): IPP MP North Meath 1886–1892
- Donogh O'Malley (1921–1968): FF TD Limerick East 1954–1968
- his nephew Desmond O'Malley (born 1939): FF/PD TD Limerick East 1968–2002
- Desmond's daughter Fiona O'Malley (born 1968): PD TD Dún Laoghaire 2002–2007, Senator 2007–2011
- Desmond's cousin Patrick O'Malley (born 1943): PD TD Dublin West 1987–1989
- Desmond's first cousin Tim O'Malley (born 1944): PD TD Limerick East 2002–2007
- his nephew Desmond O'Malley (born 1939): FF/PD TD Limerick East 1968–2002
- John M. O'Sullivan (1891–1948): FG TD Kerry/Kerry North 1923–1943
- his brother Timothy O'Sullivan (1879–1950): IPP MP East Kerry 1910–1918
- their cousin Eugene O'Sullivan (1879–1942): IPP MP East Kerry 1910
- Timothy O'Sullivan (1899–1971): FF TD Cork West 1937–1954, Senator 1957–1959
- his niece Peggy Farrell (1920–2003): FF Senator 1969–1973
Read more about this topic: Families In The Oireachtas