Extractable Nuclear Antigens - ENA 4

ENA 4

ENA 4 is a grouping of antibodies often used to screen for mixed connective tissue disease (MCTD), Sjögren's syndrome and systemic lupus erythematosus and commonly is composed of four tests:

  • anti-Sm (for SLE)
  • anti-RNP (for MCTD)
  • anti-La (for Sjögren's)
  • anti-Ro (for Sjögren's)

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