Extended Cycle Combined Hormonal Contraceptive - History

History

Before the advent of modern contraceptives, reproductive age women spent most of their time either pregnant or nursing. In modern western society women typically have about 450 periods during their lives, as compared to about 160 formerly.

Although it was evident that the pill could be used to suppress menstruation for arbitrary lengths of time, the original regimen was designed to produce withdrawal bleeding every four weeks to mimic the menstrual cycle.

Seasonale was first developed by Barr Pharmaceuticals, in collaboration with Eastern Virginia Medical School, under an agreement. The U.S. Food and Drug Administration (FDA) approved Seasonale in the United States on September 5, 2003. Barr Pharmaceuticals, its manufacturer, claimed at the time of Seasonale's approval that it would cost one dollar per pill. Seasonale is one of Barr Pharmaceuticals' 22 oral contraceptive products. Health Canada approved Seasonale in July 2007, and Paladin Labs began distributing it in Canada on January 4, 2008.

The FDA approved Lybrel for human consumption on May 22, 2007. Lybrel is currently available at pharmacies by prescription only.

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