Exfoliation has several meanings:
- Exfoliation (botany) describes the loss of leaves (or, in some cases, pieces of bark) from a plant.
- Exfoliation (cosmetology), is a cosmetic technique aimed at removing dead skin cells from the face and body.
- Exfoliation dome, a granite dome,
- Exfoliation (geology) is a weathering process.
- Exfoliation (material science) is the process responsible for breaking up particle aggregates.