Eukaryotic Translation Initiation Factor 4 Gamma
| Gene Ontology | |
|---|---|
| Molecular function | • DNA binding • translation initiation factor activity • protein binding • translation factor activity, nucleic acid binding |
| Cellular component | • cytoplasm • cytosol • eukaryotic translation initiation factor 4F complex |
| Biological process | • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay • nuclear-transcribed mRNA poly(A) tail shortening • translation • translational initiation • regulation of translational initiation • cell death • insulin receptor signaling pathway • gene expression • RNA metabolic process • mRNA metabolic process • virus-host interaction • cytokine-mediated signaling pathway • cellular protein metabolic process |
| Sources: Amigo / QuickGO | |
184.03 – 184.05 Mb
20.67 – 20.69 Mb
Eukaryotic translation initiation factor 4 gamma 1 is a protein that in humans is encoded by the EIF4G1 gene.
The protein encoded by this gene is a component of the protein complex EIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure, and recruitment of mRNA to the ribosome. Alternative splicing results in five transcript variants encoding four distinct isoforms.
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