Synthetic Ether Lipid Analogs
Synthetic ether lipid analogs have cytostatic and cytotoxic properties, probably by disrupting membrane structure and acting as inhibitors of enzymes within signal transmission pathways, such as protein kinase C and phospholipase C.
A toxic ether lipid analogue miltefosine has recently been introduced as an oral treatment for the tropical disease leishmaniasis, which is caused by leishmania, a protozoal parasite with a particularly high ether lipid content in its membranes.
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Famous quotes containing the words synthetic and/or ether:
“In every philosophical school, three thinkers succeed one another in the following way: the first produces out of himself the sap and seed, the second draws it out into threads and spins a synthetic web, and the third waits in this web for the sacrificial victims that are caught in it—and tries to live off philosophy.”
—Friedrich Nietzsche (1844–1900)
“Is this then a touch? quivering me to a new identity,
Flames and ether making a rush for my veins,
Treacherous tip of me reaching and crowding to help them,
My flesh and blood playing out lightning to strike what is hardly
different from myself,
On all sides prurient provokers stiffening my limbs,”
—Walt Whitman (1819–1892)