Estrogen Receptor
Estrogen receptors are a group of proteins found inside cells. They are receptors that are activated by the hormone estrogen (17β-estradiol). Two classes of estrogen receptor exist: ER, which is a member of the nuclear hormone family of intracellular receptors, and the estrogen G protein-coupled receptor GPR30 (GPER), which is a G protein-coupled receptor. This article refers to the former (ER).
Once activated by estrogen, the estrogen receptor is able to bind to DNA and regulate the activity of many different genes (i.e. it is a DNA-binding transcription factor). However, it also has additional functions independent of DNA binding.
Read more about Estrogen Receptor: Proteomics, Genetics, Distribution, Binding and Functional Selectivity, Signal Transduction, Research History
Famous quotes containing the word receptor:
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